All the accommodation in My Tho is within easy walking distance of the riverbank and every place will offer to organise a boat trip for you, though none seem to be able to advise on how to do it independently.
This is the only hotel in central My Tho town that is located right on the riverbank. Adjoining the night market and the long tourist boat shopping and ticketing centre, the hotel offers great views over the river. Make sure to ask for a room on the first floor as they have unobstructed views of the Mekong. While the views at Minh Quan may be higher, you don't get closer than this. The rooms are... Read our full review of Chuong Duong Hotel.
This tall, very narrow, Saigon-style mini-hotel is quite new and offers solid mid-range value along the My Tho riverfront. While the cheapest rooms are windowless, the ones with riverside views are quite good value and are well furnished and more spacious than you'd expect given the narrow nature of the building. All of the rooms come with air-con, TV, mini-fridge and hot water. The rooms are... Read our full review of Minh Quan Hotel.
The comfortable and slightly flash-looking Song Tien Hotel is a couple of blocks back from the main river and instead overlooks the Bao Dinh river. This isn't necessarily a bad thing as this smaller river enjoys quite a bit of boat traffic and is good for photos -- or just relaxing watching the boats slide by. Rooms are of a reasonable standard and are all decked out with air-con, hot water, and... Read our full review of Song Tien Hotel.
The Rang Dong is a little bit of a walk away from the rest of the offerings in My Tho and attracts a mixed crowd of Vietnamese and foreign backpackers. Staff are friendly and accommodating, but the rooms are very average -- very average. Rock hard beds combined with the traffic out front does not make for the best night of sleep and be sure to ask to be shown another if the first room is too... Read our full review of Rang Dong Mini Hotel.
This riverfront hotel has poorer rooms than the Song Tien Hotel, but the views from the upper floors do compensate somewhat as they offer expansive views over the distant river and bridge. The location is also directly opposite the riverside boardwalk with its shady cafes. Their cheapest fan rooms are on the ground floor and are pretty dire with cold water bathrooms and super soft beds. Better... Read our full review of Cong Doan Hotel.