There is no proper bus station in Sangkhom; green-and-silver local buses can pick up passengers anywhere along Route 211.
Three local buses depart for Nong Khai each day, and two head the opposite way to Loei. From Sangkhom, the bus departs for Nong Khai around 6:30, 11:30 and 16:00, costs 60 baht and takes around three hours. Along with every little village en route, it stops at Sri Chiang Mai and Tha Bo.
Buses bound for Loei pass through Sangkhom around 10:30 and 14:00. Note that a third, identical bus passes through around 18:00, but it terminates at Pak Chom and does not go on to Loei.
At Nong Khai bus station, buses to Sangkhom depart at 7:30, 11:00 and 15:00.